The body is miraculous in its ability to manufacture many different substances that are involved in maintaining good health. SAMe (S-adenosyl-methionine), which the body makes from the amino acid methionine, is one example of a molecule that is important to the moods we experience. SAMe helps form, activate, or breakdown hormones, fats, proteins, neurotransmitters, and medications.The brain and the liver usually make the necessary amount of SAMe, but for people experiencing depression, this process may be impaired. Low levels of SAMe results in decreased levels of serotonin, dopamine and other neurotransmitter activity commonly seen in clinical depression. SAMe can help boost neurotransmitter activity, bringing about improvement in mood and relief from depression.Since the 1980s, European countries, including Italy, Spain, and Germany, have been testing and using SAMe (pill form or injection) to treat depression anxiety, chronic pain, and other health conditions. SAMe is available in the United States as a dietary supplement, but it can interact with other medications. In research and in clinical practice, SAMe is well tolerated by most adults, but is not recommended for children, or women who are pregnant or breastfeeding. Therefore, it is best to use SAMe while in the care of a licensed holistic health practitioner.
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(202) 499-7535
Indigo Integrative Health Clinic
1010 Wisconsin Ave., NW, Suite #660
Washington, D.C. 20007
Hours of operation
Monday - Friday
9am - 5pm
Hours of Operation
Monday - Friday
9am - 5pm