Research Genetic Cancer Center has developed a test to explore the possibilities that a personalized treatment approach can offer you through individual testing. You are a unique person and so is your dis-ease.
PERSONALIZED CANCER TESTING
- Early detection
- Personalized treatment of cancer
- Chemosensitivity testing
R.G.C.C. Group offers a range of individualized tests from a world-class molecular oncology laboratory based in Northern Greece.
These tests can…
- Detect early signs of a developing cancer
- Help to monitor existing cancers
- Produce an individual profile of which cancer drugs and which natural substances can be used to achieve the best treatment outcomes
CIRCULATING TUMOR CELLS
CTC’s are cancer cells which have broken away from the primary tumor and have entered the blood stream where they circulate and have the potential to generate metastatic disease and secondary tumor. These cells can be isolated and identified and there is growing interest in their detection for the following purposes…
- The early detection and diagnosis of new cancers
- Monitoring existing cancers
- Prognosis – providing information about the risk of recurrence of a current or old cancer
R.G.C.C. Group offers general assays for CTC’s and for specific cancers, including breast, colorectal, prostate, malignant melonoma and sarcomas.
There is a growing interest in personalized treatments and the identification of suitable treatments that may work best for the individual with cancer. Chemosensitivity testing is one method of doing this.
Cancer doctors primary rely on the standard analysis of large treatment trials to decide which drugs to use for specific cancers. Chemosensitivity testing involves testing on individual cancer cells in the laboratory to see which drugs and which natural substances demonstrate the best response.
Chemosensitivity testing provides information and guidance about the treatments and, in particular, what treatments may be best suited to the individual in clinical practice.
The R.G.C.C. Group test is a blood test (or sometimes tissue). Tumor cells are identified and isolated from the sample for the following analysis…
- Viability testing of chemotherapy drugs
- Genetic profiling for guidance about targeted therapies e.g. monoclonal antibodies
- Viability testing (and identification of mechanisms of action) of natural substances which may be used as part of a complementary treatment strategy
The results are presented in a written report which the doctor can use to help guide treatment options and choices. In addition, R.G.C.C. Group can provide information about how an individual will ‘handle’ specific chemotherapy agents. Our genetic makeup determines whether we are ‘accumulators’ or ‘rapid metabolizers’ of certain drugs.
This can play a critical role in determining how effective a specific treatment is likely to be for us, and how significant the side effects will be. R.G.C.C. Group is a world class laboratory which specializes in medical genetics and in particular cancer genetics, providing a global service.
The tumor is consisted from several subgroups of cells (subpopulations) with different features. One of the subset actually drives the progress of the disease, the resistance to therapy and the relapse. This subset is called cancer stem cells like cells or tumor initiating cells. When a patient is treated and the cancer cells may be destroyed, then when the compatible diagnostic does not discover any signal, the cancer cells may consist a population of 10^9 to 10^12 cells. This limit defines the remission stage of a patient. At that stage only the cancer stem cells may survive and colonize into distant organs and generate metastases in time.
Hence the usage of the R.G.C.C. Group test is to detect in which therapeutic approach the cancer cell may respond and also during remission, it is essential to detect, discover and explore the features of the disseminated cancer stem cell like, in order to delay further the risk of relapse and also to generate options to treat even these kinds of cells. The main goal is to discover, analyze and screen the cancer cells in every step of the disease.
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