Accurately Diagnosing Lyme Disease

Dr. Rev. Isabel Sharkar

Dr. Isabel Sharkar, NMD, is co-founder of Indigo Integrative Health Clinic in Washington, D.C., a thriving clinic that has been serving the local community in health restoration and body optimization for over a decade. Being in constant pursuit for truth and healing Dr. Isabel graduated in 2011 from Southwest College of Naturopathic Medicine as a Doctor of Naturopathic Medicine.

Author profile

By Caroline Hoeffgen, COO, BCHC, JD | Reviewed by Dr. Isabel Sharkar, NMD | May 2026

Unmasking Lyme Disease

The Importance of Accurate Diagnosis

Accurately diagnosing Lyme disease may be challenging. Lyme disease is a tick-borne illness that can cause a range of symptoms, including fatigue, joint pain, and neurological problems. The disease is caused by the bacterium Borrelia burgdorferi, which is transmitted to humans through the bite of an infected tick. It can also be passed down from mother to newborn.Diagnosing Lyme disease can be challenging, and it is often misdiagnosed or not diagnosed at all. Conventional medicine typically relies on the ELISA and Western blot tests to diagnose Lyme disease. However, these tests are notoriously inappropriately read by the practitioner, leading to a delay in diagnosis and treatment.Functional medicine takes a different approach to diagnosing Lyme disease. Functional medicine practitioners use a range of tests, including the polymerase chain reaction (PCR) test and specialized Lyme panel tests by specialized Lyme labs, to detect the presence of Borrelia burgdorferi and possible co-infections in the body. These tests are more sensitive than the ELISA and Western blot tests and can detect the presence of the bacterium even in the early stages of the disease.Additionally, functional medicine practitioners take a comprehensive approach to Lyme disease diagnosis and treatment, taking into account the patient's medical history, lifestyle, and environmental factors. They may also use other tests, such as a CD57 test, to evaluate the patient's immune function and determine the most appropriate treatment plan.In contrast, conventional medicine that is not Lyme literate may overlook the possibility of Lyme disease altogether or dismiss the patient's symptoms as psychosomatic. This can result in a delay in diagnosis and treatment, leading to more severe and chronic symptoms in the long run.In conclusion, Lyme disease is a complex illness that can be challenging to diagnose and treat. Functional medicine offers a more comprehensive approach to Lyme disease diagnosis and treatment, using a range of tests and taking into account the patient's medical history and lifestyle. It is essential to consult with a Lyme literate practitioner if you suspect that you may have Lyme disease, as early diagnosis and treatment can improve outcomes and reduce the risk of chronic symptoms.Here are some other Lyme resources to check out:

Medical Disclaimer

This content is provided by Indigo Integrative Health Clinic for educational purposes only. It does not constitute medical advice, a diagnosis, or a treatment recommendation, and does not establish a provider-patient relationship. Individual health conditions vary — information presented here may not apply to your specific situation. Always consult a qualified, licensed healthcare provider before making decisions about your health, medications, supplements, or treatment plan.

Featured in
Related articles

Continue reading

View all articles

Hashimoto's is diagnosed by combining findings, not one test: thyroid antibodies (TPO, sometimes thyroglobulin), thyroid function (TSH and free T4), symptoms, and often an ultrasound. A normal TSH does not rule it out, and a low-positive antibody is not always disease. Found early, before the gland is damaged, there is the best chance to protect it and feel better.

There is no single Hashimoto's diet, but a few moves have real evidence. Correct the nutrient gaps you can measure, like iron, selenium, and vitamin D. Get your iodine to the right level, which takes an assessment, not one test. And cut a food only for a real reason, like a positive celiac test or too much iodine. Assess first, then personalize.

Lyme disease shares key symptoms with fibromyalgia, multiple sclerosis, and chronic fatigue syndrome, so it can be mistaken for any of them. It is also over-diagnosed in people who do have one of those conditions. The honest answer is that Lyme is worth confirming or ruling out with a knowledgeable clinician, not assumed in either direction.