The CDC classifies Washington DC, Maryland, and Virginia as high-incidence areas for Lyme. Standard two-tier blood testing catches only 22 to 36 percent of early infections, so a negative result does not rule Lyme out when symptoms are present. Free state and county programs identify a tick's species but do not test it for disease, and broader co-infection testing is not routinely ordered.
Yes, and it is climbing fast. Maryland's reported Lyme cases have almost tripled since 2020, and the CDC classifies Washington DC, Maryland, and Virginia as high-incidence areas. Picture Lyme country and most people name New England, but the mid-Atlantic has been in the same category for years. The places on that list account for roughly 90 percent of reported US cases.
The true number is close to ten times what gets counted. The CDC estimates about 476,000 people are diagnosed and treated for Lyme each year nationally, far more than the case counts that make the news.
| Place | Reported Cases | Rate per 100,000 (2022) | Compared with the Country |
|---|---|---|---|
| Maryland | 2,463 (2023), over 3,000 (2024) | 32.9 | About 1.7 times national |
| Virginia | 1,403 (2022) | 16.3 | Just below national |
| Washington DC | 77 (2022) | 11.2 | Below national |
| United States | 62,551 (2022), over 89,000 (2023) | 18.9 | National baseline |
The DMV sits at the lower end of that list. Maine and Vermont run several times higher. Being on it still matters, because the CDC tracks Lyme here differently than it tracks Texas or Arizona.
Tick-bite ER visits are running at their highest since 2017, and the DMV sits in the region leading the country. The coverage calls it a Northeast surge, but the CDC's Northeast for this data includes Washington DC, Maryland, Virginia, and West Virginia, so those headlines have been about here all along. The CDC reported the highest weekly rates for this point in the year since 2017 in every region except the South Central states.
Some of the rise in reported cases comes from a 2022 change in how states count Lyme, and some may reflect greater awareness. ER data track visits for tick bites rather than Lyme diagnoses, but those visits are up sharply.
Ticks carrying Lyme now live in Rock Creek Park, which puts the middle of the District on the same list as Shenandoah. A CDC and National Park Service study documented infected nymphs in park land across the region.
Most exposure happens at the forest edge, not deep in the woods. Leaf litter, tall grass, and deer paths are where ticks wait. Those run through backyards across Fairfax, Montgomery, and Loudoun counties. Maryland tick monitoring from 2020 through 2024 found Lyme bacteria in roughly 5 to 20 percent of the young ticks it collected.
The nymph that transmits most Lyme cases is about the size of a poppy seed, which is why so many people never notice or recall a bite. Within Virginia, the highest reported rates are in the rural southwest rather than the northern suburbs. Exposure follows habitat, not population.
IDSA and the CDC point to a rough window, generally 36 to 48 hours before Lyme risk climbs. ILADS holds that no minimum attachment time has ever been established for Lyme transmission risk, so no clock tells you that you are safe.
All three are working from the same animal research, which tested ticks at set intervals starting at 24 hours. Transmission happened at every interval, including the shortest. It was less frequent early, then climbed steeply by 42 and 48 hours. IDSA and the CDC use 36 hours as the point worth acting on. ILADS notes that Lyme was transmitted at the shortest duration anyone has measured (24 hours), so no study has established an attachment time below which it cannot transmit.
ILADS draws a different line from the same data. Nobody has tested an attachment time short enough to come back clean, so there is no evidence that early transmission does not happen. In other animal research, a tick that fed on one host, dropped off, and reattached to a second one passed Lyme to the second host far faster. Nothing about a tick on your skin tells you whether it had fed before.
That uncertainty is about Lyme. The other infections a tick carries run on their own clocks, set by separate research, and several transmit faster than Lyme. Getting a tick off the same day puts the odds in your favor. It does not clear you, and no clinician can promise that it does.
The clock runs differently for every pathogen a tick can carry.
Anaplasma and Babesia both matter in DMV blacklegged ticks, but Babesia deserves special attention because doxycycline does not treat it. The tick-bite antibiotic clinics reach for, doxycycline, treats Lyme and Anaplasma but has no effect on Babesia.
Babesia is a parasite related to malaria, not a bacterium, so it needs antiparasitic treatment. Someone carrying both can finish a full course of Lyme antibiotics and stay sick, which is one of the more common ways a case gets written off as treatment failure.
Babesia arrived in this region recently and it is spreading. A 2025 study in the Journal of Medical Entomology tracked both the ticks and the human cases.
Case counts are still small, and the authors note that babesiosis may be underrecognized as it emerges in a region where clinicians have historically encountered it less often. Each co-infection has a pattern worth knowing, shown below.
| Infection | Symptoms that stand out | On a standard Lyme test | Treated by Lyme antibiotics? |
|---|---|---|---|
| Babesia (a parasite, like malaria) | Drenching night sweats, shortness of breath, deep fatigue, chills | Not included, needs its own test | No. A parasite, needs antiparasitic treatment |
| Anaplasma (bacteria in white blood cells) | High fever, severe headache, muscle aches, low white-cell and platelet counts | Not included, needs its own test | Usually. Doxycycline, the same drug used for early Lyme |
| Ehrlichia (bacteria in white blood cells) | Fever, headache, muscle aches, nausea, rash more often in children | Not included, needs its own test | Usually. Doxycycline, the same drug used for early Lyme |
| Borrelia miyamotoi (a relapsing-fever bacterium) | Fever that comes and goes, headache, chills | Not included, needs its own test | Usually. Responds to similar antibiotics |
| Powassan virus (a virus, not a bacterium) | Fever, headache, vomiting, confusion or seizures in severe cases | Not included, needs its own test | No. No antibiotic treats a virus |
Bartonella appears on almost every tick-borne illness list, and US published research does not establish it as tick-transmitted. It can still cause real illness, including cognitive and mood symptoms. The known routes are cat scratches and bites, fleas, and body lice. For the fuller picture on which infections a standard panel skips, see the co-infections a standard Lyme test was never built to find.

Virginia is one of the five states with the highest alpha-gal antibody rates in the country, according to CDC data published in July 2026. Unlike the co-infections above, alpha-gal is an allergy rather than an infection, and it comes from the lone star tick, not the blacklegged tick that carries Lyme. Lone star ticks are widespread across Virginia, Maryland, and Washington DC.
A positive blood test means your immune system has reacted to alpha-gal, which is not the same as having the allergy. A diagnosis needs both a positive test and a reaction that fits the alpha-gal pattern, usually hives or stomach trouble a few hours after eating red meat. Our guide to alpha-gal syndrome symptoms goes deeper.
Permethrin on clothing kills ticks on contact. Repellent on skin only turns them away. Both work, at different points, which is why the CDC recommends layering what you wear, what you put on skin, and what you do when you come back inside.
Before you go out:
While you are out:
Within two hours of coming inside:
Around your house:
Remove it with fine-tipped tweezers: grasp close to the skin, pull straight up, and do not throw it away. Clean the area, then take four steps.
A saved tick provides context, not a diagnosis. A positive tick carries roughly five times the risk of a negative one, and a swollen, positive tick reached about one case in seven in one European study. But a positive does not confirm transmission and a negative does not clear you, so the CDC says a tick result should not drive treatment on its own.
The first step after a bite is not a pill, it is an early conversation with a Lyme-literate clinician, ideally within days. What type of prophylaxis fits depends on the tick, how long it fed, and whether you were bitten in a high-risk area. The two major guidelines read the same 2001 trial and disagree.
Acting early matters more than the debate. An untreated infection can spread from the bite site to the joints, heart, or nervous system, and a case caught in the first weeks is usually simpler to treat than one found months later. One caveat applies either way: a preventive course that does not fully clear the infection can still blunt your antibody response, which makes the standard test harder to read later.
At Indigo, we start from the full picture, the tick, your timeline, your symptoms, and your history, rather than a single rule, and we lean toward early, thorough treatment over wait-and-see when the details call for it. We cover what untreated Lyme and its co-infections can lead to separately.
The best place to start is a full assessment with a Lyme-literate clinician in the DMV, not the standard panel alone. We encourage testing both the tick and yourself, because they answer two different questions.
Testing the tick:
Testing yourself:
The two questions patients most want answered, do I have this and is it gone, both sit outside what the standard panel can do.
So a negative test does not rule Lyme out, and it should not end the conversation while symptoms persist. If you were bitten here and you are unwell, see a Lyme-literate clinician, one who specializes in tick-borne illness. Which broader panels make sense depends on your symptoms, timeline, and exposure. We wrote more on what to do when your Lyme test comes back negative and what each Lyme test can and cannot detect.
You live in one of the highest-exposure regions in the country, and the test most likely to be run on you is least reliable in the earliest stage of infection. That gap is structural. A fifteen-minute visit and a single antibody panel cannot carry a complex tick-borne case, and patients across the DMV get stranded between what the research shows about testing limits and what a routine workup does. Nobody is acting in bad faith. The tools are narrower than the problem.
Indigo Integrative Health Clinic is a telehealth practice based in Georgetown, working with patients across the DMV on Lyme and tick-borne illness. Visits are fully virtual, so you can be treated from DC, Maryland, or Virginia without driving to our clinic. Our IV Lounge is in Georgetown for the treatments that happen in person. A complimentary Discovery Call is where every Indigo patient starts. It is a 20-minute screening call, and a team member walks through your symptom history, your past testing, and what you have already tried. You come away with a clear read on whether your case is one we can help with, and what a fuller workup would look for. It costs nothing and commits you to nothing. If there is a fit, we talk about what working together looks like. Book a free Discovery Call.
If you want to evaluate a provider first, start with finding a Lyme-literate clinician in DC, Maryland, and Virginia.
This content is provided by Indigo Integrative Health Clinic for educational purposes only. It does not constitute medical advice, a diagnosis, or a treatment recommendation, and does not establish a provider-patient relationship. Individual health conditions vary — information presented here may not apply to your specific situation. Always consult a qualified, licensed healthcare provider before making decisions about your health, medications, supplements, or treatment plan.
Bartonella is a bacterial infection that often appears alongside Lyme. In the US there is no current evidence that ticks transmit it, and the question is still under investigation. The proven routes are cat scratches and bites, cat-flea feces, and body lice. It is hard to detect, which is why a thorough Lyme workup checks for it properly.
Babesia is a malaria-like parasite carried by the same tick that carries Lyme. Because it is a parasite and not a bacterium, the antibiotics typically used for Lyme have no effect on it. It is seldom tested for, so people can finish Lyme treatment, still feel sick, and not understand why.
The CDC classifies Washington DC, Maryland, and Virginia as high-incidence areas for Lyme. Standard two-tier blood testing catches only 22 to 36 percent of early infections, so a negative result does not rule Lyme out when symptoms are present. Free state and county programs identify a tick's species but do not test it for disease, and broader co-infection testing is not routinely ordered.
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