
Dr. Isabel Sharkar, NMD, is co-founder of Indigo Integrative Health Clinic in Washington, D.C., a thriving clinic that has been serving the local community in health restoration and body optimization for over a decade. Being in constant pursuit for truth and healing Dr. Isabel graduated in 2011 from Southwest College of Naturopathic Medicine as a Doctor of Naturopathic Medicine.

Caroline serves as Chief Operating Officer of Indigo Integrative Health Clinic, where she drives the expansion of Indigo’s pioneering root-cause approach to medical care.
Drawing on her extensive experience as a Parsley Health provider, educator and board-certified Health Coach, Caroline combines operational leadership with clinical insight to advance Indigo’s mission of delivering transformative, personalized care.
Chronic illness is rarely just one problem. It's a cascade — damaged cells, overwhelmed detox pathways, neurological strain, and persistent inflammation feeding into each other.
The PK Protocol addresses all of it at the cellular level.
Key Takeaways
The PK Protocol is a comprehensive IV therapy built around Phosphatidylcholine (PC) — a phospholipid that forms the structural foundation of every cell membrane in the body.
When cell membranes are damaged — through chronic infection, toxin exposure, inflammation, or oxidative stress — cellular communication breaks down. Nutrients can't get in. Waste can't get out. Energy production suffers. And the downstream effects ripple through every system in the body.
The PK Protocol repairs this foundation, restoring the cellular integrity that complex chronic illness quietly erodes.
Phosphatidylcholine is the primary therapeutic agent in the PK Protocol. Here's what it does:
Glutathione is a critical component of the PK Protocol — and one of the most important molecules in the body for managing oxidative stress and immune function.
Glutathione levels are frequently depleted in patients with chronic illness, making IV replenishment particularly impactful.
The PK Protocol also includes a carefully selected combination of cofactors that work alongside PC and glutathione to support:
This is what distinguishes the PK Protocol from a single-nutrient IV — it addresses multiple interconnected systems simultaneously.
The PK Protocol is particularly well-suited for individuals dealing with:
If you've tried other approaches without meaningful improvement, cellular-level repair may be the missing piece.
Complex chronic illness requires a complex solution — one that addresses root causes rather than managing symptoms in isolation.
The PK Protocol does exactly that: restoring the cellular foundation that chronic illness disrupts, supporting the body's own capacity to detoxify, repair, and heal.
If you're living with a condition that conventional medicine hasn't been able to resolve, the PK Protocol may be worth exploring.
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Questions? Reach us at discovery@indigohealthclinic.com or (202)840-6622, Monday–Friday, 9AM–5PM EST.
This content is provided by Indigo Integrative Health Clinic for educational purposes only. It does not constitute medical advice, a diagnosis, or a treatment recommendation, and does not establish a provider-patient relationship. Individual health conditions vary — information presented here may not apply to your specific situation. Always consult a qualified, licensed healthcare provider before making decisions about your health, medications, supplements, or treatment plan.
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