NAD+ Injections: A Faster Way to Support Energy, Focus, and Longevity

Dr. Rev. Isabel Sharkar

Dr. Isabel Sharkar, NMD, is co-founder of Indigo Integrative Health Clinic in Washington, D.C., a thriving clinic that has been serving the local community in health restoration and body optimization for over a decade. Being in constant pursuit for truth and healing Dr. Isabel graduated in 2011 from Southwest College of Naturopathic Medicine as a Doctor of Naturopathic Medicine.

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Caroline Hoeffgen

Caroline serves as Chief Operating Officer of Indigo Integrative Health Clinic, where she drives the expansion of Indigo’s pioneering root-cause approach to medical care.

Drawing on her extensive experience as a Parsley Health provider, educator and board-certified Health Coach, Caroline combines operational leadership with clinical insight to advance Indigo’s mission of delivering transformative, personalized care.

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By Caroline Hoeffgen, COO, BCHC, JD | Reviewed by Dr. Isabel Sharkar, NMD | May 2026

NAD+ levels drop by as much as 65% between the ages of 30 and 70. If you're feeling burned out, foggy, or stuck in low gear despite doing everything right — this may be why.

NAD+ injections offer a fast, flexible way to replenish levels and keep your cells firing on all cylinders.

 

Key Takeaways

  • NAD+ fuels over 500 enzymatic reactions and is essential for energy, DNA repair, and brain function
  • Levels decline significantly with age, contributing to fatigue, cognitive decline, and metabolic dysfunction
  • NAD+ injections deliver a targeted boost in minutes — no 6-8 hour IV session required
  • They work best as maintenance between NAD+ IV therapy sessions, or as a standalone option for busy schedules
  • NAD+ therapies are not suitable for anyone with a history of cancer or active cancer

What Is NAD+ and Why Does It Matter?

NAD+(nicotinamide adenine dinucleotide) is one of the most important molecules in the body — involved in over 500 enzymatic reactions that drive energy production, DNA repair, and mitochondrial health.

Despite its importance, NAD+ levels decline dramatically with age. Research shows levels can drop by as much as 65% between ages 30 and 70, contributing to fatigue, brain fog, and metabolic dysfunction.

Restoring and maintaining NAD+ levels is one of the most evidence-supported strategies in longevity and cellular health.

 

What Are NAD+ Injections?

NAD+ injections are subcutaneous shots that deliver NAD+ directly into the body in just a few minutes.

They are not a replacement for NAD+ IV therapy — which remains one of the most comprehensive ways to restore levels. But for those who want consistent support between IV sessions, or who can't commit to a 6-8 hour infusion, injections offer a practical and effective alternative.

Think of them as a maintenance tool: keeping your levels optimized in between deeper replenishment.

What Are the Benefits of NAD+ Injections?

 

Fast and convenient — A full boost in minutes, no long IV session required

Ideal for maintenance — Keeps NAD+ levels optimized between IV therapy sessions

Energy and focus support — Helps combat fatigue, brain fog, and sluggishness

Mitochondrial health — Enhances cellular function, metabolism, and longevity

Flexible dosing — Can be used several times per week based on your individual goals

 

Who Should Consider NAD+ Injections?

 

NAD+ injections are well-suited for:

Busy professionals and entrepreneurs who can't commit to lengthy IV sessions
Athletes and active individuals needing quick recovery and sustained energy
Patients looking to extend the benefits of NAD+ IV therapy between sessions
Anyone experiencing brain fog, fatigue, or metabolic sluggishness
Those pursuing longevity and anti-aging strategies to keep cells functioning optimally.

 

Important: NAD+ therapies are not suitable for anyone with a history of cancer or active cancer. Please discuss your full health history with your Indigo provider before starting.

 

How to Incorporate NAD+ Injections Into Your Routine

 

There's no single protocol — your Indigo provider will tailor the approach to your needs. Common patterns include:

 

Several times per week for sustained NAD+ levels and ongoing support

Between IV sessions to maintain and extend the benefits of your infusions

As needed when feeling fatigued, mentally drained, or in need of a cellular reset

 

For best results, pair NAD+ therapy with regular movement, nutrient-rich foods, quality sleep, and stress management. NAD+ amplifies the benefits of these foundational practices — it doesn't replace them.


Final Thoughts

 

Maintaining NAD+ levels isn't a one-time event — it requires consistent replenishment as levels naturally decline with age.

Whether you're looking to extend the results of your IV therapy or simply need a smarter, faster option that fits your schedule, NAD+ injections are worth exploring.

Talk to your Indigo provider to find out if they're the right fit for your health goals.

Book a free Discovery Call

  

Questions? Reach us at discovery@indigohealthclinic.com or (202) 840-6622, Monday–Friday, 9AM–5PM EST.

Medical Disclaimer

This content is provided by Indigo Integrative Health Clinic for educational purposes only. It does not constitute medical advice, a diagnosis, or a treatment recommendation, and does not establish a provider-patient relationship. Individual health conditions vary — information presented here may not apply to your specific situation. Always consult a qualified, licensed healthcare provider before making decisions about your health, medications, supplements, or treatment plan.

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